Big City was briefly swept by a city-wide crime wave, in the early 1940s. This was ended by the efforts of three unidentified youths, calling themselves the "Blue Boys", and afterward Big City was among the safest cities in America to live and work. Local crime persisted, of course, with the occasional bank or warehouse robbery, and car theft rings, that any large town endures, but there was little of the sort of colorful, dramatic crimes that were, at that time, becoming commonplace in Metropolis or Gotham City. Here the criminal class consisted mainly of inheritance embezzlers, counterfeiters, gem thieves, and sports cheats.
Municipal government corruption was a problem, as seen in the case of Food Commissioner Calcum, which was also resolved through the efforts of the same three anonymous juvenile vigilantes, the "Blue Boys".
- Big City may have been the site of a fight between Superboy and Risk. A waste disposal dumpster at the scene of the fight identifies Big City, though this does not necessarily mean that this is where the fight took place. 
- Another city called "Big City" was featured in National Comics #42 as the home of Carnie Calahan. That city is located in Pennsylvania.
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