Crime does not have it's origins solely confined to mankind. Between the discovery of alien races and advanced civilizations, the reality is that vice is universal and not merely center within humanity.
On the distant planet of Colu, artificial intelligence was created in the form of a computer mind more advanced than any on that planet. This artificial life replicated itself until it became that world's dominant life form, enslaving its very creators.
But expansion and domination of the planet was not enough. The A.I. created a humanoid machine more advanced than itself. This "Brainiac" was built to expand the artificial intelligence's empire beyond Colu. Brainiac traveled from one world to another, using Coluan technology to miniaturize whole cities and populations for further study.
In years to come, the super computer that ruled Colu was destroyed, but Brainiac continued in the purpose for which he had been built -- to conquer the universe. This brought the last surviving super computer of Colu to Earth where he was confronted with the last surviving member of the Kryptonian race.
Superman had since learned that the original Coluan scientists did more than create artificial intelligence. They created artificial envy, artificial greed and artificial hatred. That makes Brainiac more than an enemy of Superman. He is an enemy of every living thing. 
- Enhanced Intellect: Brainiac may certainly be the most inventive, creative, demonic and twisted mind in this universe and otherwise. On Earth, although not outsmarted merely outplayed, Brainiac is constantly at the helm of planetary threats.
- Computer Operation: Brainiac is in constant control over his cloned body and if he chose to further replicate himself he would be able to control them as well; furthermore, despite thousands of Mister Minds distributed across the globe Brainiac can seize control of them individually and manipulate them.
- Deception: He masterminded Earth's newest threat, one that came under the guise of the evolution of humankind.
- Robotic Engineering: Brainiac is a cloned artificial intelligence that replicated itself to conquer a planet of it's creators.
- Science: Being a being of incredible intellect and skill, Brainiac's knowledge is primarily stepped into science and it's physical applications such as the surgery to remove Aquaman's brain.
- 8 Appearances of Brainiac (Justice)
- 6 Images featuring Brainiac (Justice)
- Quotations by or about Brainiac (Justice)
- Character Gallery: Brainiac (Justice)