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I didn't say I could explain it, Doctor. But somehow, someone has managed to murder that which was not alive.
What the Bright really don't understand, Lady Celia, is that it is appetite which gives their lives purpose. It's the hunger to lean, and grow, and live, that drives them on. When you take the cure, it takes your appetite away. So the very point of living disappears at the precise moment that you're given an endless slice of lifetime to use up.