Chemo was working under the orders of the Brain and threatened Bialya into submission after defeating its navy and devouring a nuclear missile. He was opposed by Batman and Aquaman, in which during the battle Chemo infected Batman with its phyllosilicates. Chemo was soon defeated as Batman was able to eliminate the missile which breaks up Chemo.

Chemo later battled Batman again and the Metal Men, whom the latter helped in defeating Chemo.