The Gotham River is a river that separates Gotham City with Gotham County, hence its name. It is the main water source for Gotham City and its inhabitants.
Some events of major significance have taken place during winter, as the river's waters are frozen. Certain winter night, the troubled creature known as Blockbuster fell to the frozen waters of the Gotham River, after he saved a suicidal girl. He was presummed dead. On another occasion, the Gotham City Police Department dragged out of the waters a man encased in solid ice, unaware that the man inside was Mister Freeze and that he had chosen the cold waters to preserve his frosty shell while he hibernated.
- On the No Man's Land map, the Gotham River was the river separating the entire city from the mainland, but in the Nolanverse and New 52 redesigns, it is the river separating the south island from the rest of the city.