New Gods are vulnerable to a substance called Radion. It source is unknown and its effects are toxic only in sustained amounts or after explosive exposure. The average New God can be slain by an application of Radion from a Radion blaster or bomb. More advanced beings such as Mister Miracle, protected by their mother box, armor and sheer toughness, have been known to take two hits and survive. Radion may require the mysterious Element X to create.